Methanol → 1-N-Boc-4-Piperidinecarboxylic acid methyl ester

HRID 684207Notes

Reaction equation

HRID 684207 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:12](=[O:13])[OH:14])[CH2:15][CH2:16]1.[CH3:17][Si:18]([CH:19]=[N+:20]=[N-:21])([CH3:22])[CH3:23].[CH3:24][OH:25].[Cl:26][CH2:27][Cl:28]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:12](=[O:13])[O:14][CH3:17])[CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 167693TrimethylsilyldiazomethaneHCID 3928711-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acid

Product 1

HCID 3928701-N-Boc-4-Piperidinecarboxylic acid methyl ester

Sources & evidence

ORD record
ord-98a96bc8264948f1bec09d3ba5314fbb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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