Potassium Cation → Ethyl 2-(4-cyclopropanesulfonylphenyl)-2-(2,4-difluoro-phenoxy)acetate

HRID 684241Notes

Reaction equation

HRID 684241 reaction equation
[C:10](=[O:11])([O-:12])[O-:13].[CH2:16]([CH3:17])[O:18][C:19]([CH:20]([c:21]1[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH:30]2[CH2:31][CH2:32]2)[cH:25][cH:26]1)[Br:33])=[O:34].[CH3:35][C:36]#[N:37].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[F:1][c:2]1[c:3]([OH:9])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[K+:14].[K+:15]>>[F:1][c:2]1[c:3]([O:9][CH:20]([C:19]([O:18][CH2:16][CH3:17])=[O:34])[c:21]2[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH:30]3[CH2:31][CH2:32]3)[cH:25][cH:26]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 1230512,4-DifluorophenolHCID 59610021Ethyl 2-bromo-2-(4-cyclopropylsulfonylphenyl)acetate

Product 1

HCID 59610052Ethyl 2-(4-cyclopropanesulfonylphenyl)-2-(2,4-difluoro-phenoxy)acetate

Sources & evidence

ORD record
ord-8b5fb13017ad4be09bb4eb46d601cefc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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