Trifluoroacetic acid → 4-Methyl-2-[3-[(6-propan-2-yl-3-pyridinyl)methylcarbamoyl]-4-[4-(trifluoromethoxy)phenyl]sulfonylpiperazin-1-yl]-1,3-thiazole-5-carboxylic acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([CH3:46])[n:10][c:11]([N:13]2[CH2:14][CH:15]([C:33]([NH:34][CH2:35][c:36]3[cH:37][n:38][c:39]([CH:42]([CH3:43])[CH3:44])[cH:40][cH:41]3)=[O:45])[N:16]([S:19](=[O:20])(=[O:21])[c:22]3[cH:23][cH:24][c:25]([O:28][C:29]([F:30])([F:31])[F:32])[cH:26][cH:27]3)[CH2:17][CH2:18]2)[s:12]1.[OH:47][C:48]([C:49]([F:50])([F:51])[F:52])=[O:53]>>[O:5]=[C:6]([OH:7])[c:8]1[c:9]([CH3:46])[n:10][c:11]([N:13]2[CH2:14][CH:15]([C:33]([NH:34][CH2:35][c:36]3[cH:37][n:38][c:39]([CH:42]([CH3:43])[CH3:44])[cH:40][cH:41]3)=[O:45])[N:16]([S:19](=[O:20])(=[O:21])[c:22]3[cH:23][cH:24][c:25]([O:28][C:29]([F:30])([F:31])[F:32])[cH:26][cH:27]3)[CH2:17][CH2:18]2)[s:12]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3b6880bdced84592ac1b7a56b7859ea4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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