Sodium ion → 4-[2-(3,5-Difluoro-benzyloxy)-pyrimidin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][N:28]([c:31]2[n:32][c:33]([Cl:37])[n:34][cH:35][cH:36]2)[CH2:29][CH2:30]1.[F:1][c:2]1[cH:3][c:4]([CH2:5][OH:6])[cH:7][c:8]([F:10])[cH:9]1.[H-:16].[Na+:17].[O:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1.[OH2:38]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][O:6][c:33]2[n:32][c:31]([N:28]3[CH2:27][CH2:26][N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:30][CH2:29]3)[cH:36][cH:35][n:34]2)[cH:7][c:8]([F:10])[cH:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-339e5c57ca2e4cfcbdfc18ab560d03a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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