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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 684531Generated: October 30, 2026

Tetrahydrofuran → 2-(2-Chlorophenylamino)-3,4-difluoro-5-trimethylsilanylethynylbenzoic acid methyl ester

https://huagongshe.com/reaction/684531

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant5-Bromo-2-(2-chlorophenylamino)-3,4-difluorobenzoic acid methyl esterHCID 86596771—
Product2-(2-Chlorophenylamino)-3,4-difluoro-5-trimethylsilanylethynylbenzoic acid methyl esterHCID 86596772—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-9dc13fdf91ce448b8bfa17901f5f50a4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)