Dichloromethane → 1-[2-Fluoro-5-bromobenzyloxy]-3-(piperidin-3-yl)propane
Reaction equation
[CH2:34]([Cl:35])[Cl:36].[F:8][c:9]1[c:10]([CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH:16]2[CH2:17][N:18]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:19][CH2:20][CH2:21]2)[cH:29][c:30]([Br:33])[cH:31][cH:32]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[F:8][c:9]1[c:10]([CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH:16]2[CH2:17][NH:18][CH2:19][CH2:20][CH2:21]2)[cH:29][c:30]([Br:33])[cH:31][cH:32]1Participants
4
Sources & evidence
- ORD record
- ord-be6cf2802dfe41c3859001a3f6f230ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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