1,2-Dichloroethane → 1-{2-[4-({[5-chloro-6-(hydroxymethyl)-3-pyridinyl]methyl}amino)-1-piperidinyl]ethyl}-7-fluoro-1,5-naphthyridin-2(1H)-one
Reaction equation
[C:33]([O:34][BH-:35]([O:36][C:37](=[O:38])[CH3:39])[O:40][C:41](=[O:42])[CH3:43])(=[O:44])[CH3:45].[Cl:22][c:23]1[cH:24][c:25]([CH:31]=[O:32])[cH:26][n:27][c:28]1[CH2:29][OH:30].[Cl:47][CH2:48][CH2:49][Cl:50].[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][n:10]2[c:11](=[O:21])[cH:12][cH:13][c:14]3[n:15][cH:16][c:17]([F:20])[cH:18][c:19]23)[CH2:6][CH2:7]1.[Na+:46]>>[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][n:10]2[c:11](=[O:21])[cH:12][cH:13][c:14]3[n:15][cH:16][c:17]([F:20])[cH:18][c:19]23)[CH2:6][CH2:7]1)[CH2:31][c:25]1[cH:24][c:23]([Cl:22])[c:28]([CH2:29][OH:30])[n:27][cH:26]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fcfd302347c04374af885c437cc0244b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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