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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 684729Generated: October 30, 2026

Methyl 2-chloropyrimidine-5-carboxylate → 2-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-benzyloxy}-pyrimidine-5-carboxylic acid methyl ester

https://huagongshe.com/reaction/684729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-chloropyrimidine-5-carboxylateHCID 12627752—
Reactant3-(2-Chloro-4-hydroxymethyl-phenyl)-2-(2-chloro-pyridin-4-yl)-1,1,1-trifluoro-butan-2-olHCID 25254449—
Product2-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-benzyloxy}-pyrimidine-5-carboxylic acid methyl esterHCID 72310576—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-aaa2829111e842d69d633f0f78a504ca
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)