Formic Acid → 4-(4-{3-[1-(2,6-Dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-pyrazol-1-yl)-piperidine-1-carbaldehyde
Reaction equation
[B-:35]([F:36])([F:37])([F:38])[F:39].[CH:32](=[O:33])[OH:34].[CH:57]([N:58]([CH2:59][CH3:60])[CH:61]([CH3:62])[CH3:63])([CH3:64])[CH3:65].[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18](-[c:21]4[cH:22][n:23][n:24]([CH:26]5[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]5)[cH:25]4)[cH:19][c:20]23)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8].[Cl:66][CH2:67][Cl:68].[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18](-[c:21]4[cH:22][n:23][n:24]([CH:26]5[CH2:27][CH2:28][N:29]([CH:32]=[O:33])[CH2:30][CH2:31]5)[cH:25]4)[cH:19][c:20]23)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e41d7320b7484157b73904af5a8681c2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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