2-Methoxyethylamine → 5-(((2-Methoxyethyl)amino)methyl)pyridine-3-boronic acid pinacol ester

HRID 684975Notes

Reaction equation

HRID 684975 reaction equation
[CH3:36][C:37]1([CH3:52])[O:38][B:39]([c:44]2[cH:45][c:46]([CH:50]=[O:51])[cH:47][n:48][cH:49]2)[O:40][C:41]1([CH3:42])[CH3:43].[CH3:53][O:54][CH2:55][CH2:56][NH2:57].[CH:1]1([CH2:2][NH:3][CH2:4][c:5]2[cH:6][c:7](-[c:8]3[cH:9][c:10]4[c:11]([c:12]([C:13]([NH2:14])=[O:15])[cH:16]3)[nH:17][cH:18][c:19]4[CH:20]3[CH2:21][CH2:22][N:23]([S:24]([CH2:25][CH3:26])(=[O:27])=[O:28])[CH2:29][CH2:30]3)[cH:31][n:32][cH:33]2)[CH2:34][CH2:35]1>>[CH3:36][C:37]1([CH3:52])[O:38][B:39]([c:44]2[cH:45][c:46]([CH2:50][NH:57][CH2:56][CH2:55][O:54][CH3:53])[cH:47][n:48][cH:49]2)[O:40][C:41]1([CH3:42])[CH3:43]

Participants

4

Reactant 3

HCID 80182-MethoxyethylamineHCID 49926405-(Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbaldehydeHCID 577327605-(5-{[(cyclopropylmethyl)amino]methyl}-3-pyridinyl)-3-[1-(ethylsulfonyl)-4-piperidinyl]-1H-indole-7-carboxamide

Product 1

HCID 574157115-(((2-Methoxyethyl)amino)methyl)pyridine-3-boronic acid pinacol ester

Sources & evidence

ORD record
ord-52500cd427fd4c38b75108b15cb66130
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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