Dimethyl Sulfoxide → rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-4-fluoro-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid (4-carbamoyl-2-fluoro-phenyl)-amide
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([F:41])[c:6]([NH:9][C:10](=[O:11])[CH:12]2[CH:13]([c:33]3[c:34]([F:40])[c:35]([Cl:39])[cH:36][cH:37][cH:38]3)[C:14]3([C:15](=[O:25])[NH:16][c:17]4[cH:18][c:19]([Cl:24])[cH:20][c:21]([F:23])[c:22]43)[CH:26]([CH2:28][C:29]([CH3:30])([CH3:31])[CH3:32])[NH:27]2)[cH:7][cH:8]1.[CH3:46][S:47]([CH3:48])=[O:49].[Na+:45].[OH-:44].[OH:42][OH:43]>>[C:1]([NH2:2])([c:3]1[cH:4][c:5]([F:41])[c:6]([NH:9][C:10](=[O:11])[CH:12]2[CH:13]([c:33]3[c:34]([F:40])[c:35]([Cl:39])[cH:36][cH:37][cH:38]3)[C:14]3([C:15](=[O:25])[NH:16][c:17]4[cH:18][c:19]([Cl:24])[cH:20][c:21]([F:23])[c:22]43)[CH:26]([CH2:28][C:29]([CH3:30])([CH3:31])[CH3:32])[NH:27]2)[cH:7][cH:8]1)=[O:42]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7d6fef0cf3814b7294e3ea1a2f1b701f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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