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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 685184Generated: October 30, 2026

1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-(3-oxo-3,4-dihydro pyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea

https://huagongshe.com/reaction/685184

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 2733265—
Reactant8-(4-amino-3-fluorophenoxy)pyrido[2,3-b]pyrazin-3(4H)-oneHCID 46900932—
Product1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-(3-oxo-3,4-dihydro pyrido[2,3-b]pyrazin-8-yloxy)phenyl)ureaHCID 44131711—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-b7a5d22dc3984daeae24090983aa3580
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)