Thionyl Chloride → HCID 86696919, compound

HRID 68541Notes

Reaction equation

HRID 68541 reaction equation
[C:1]1([N:7]2[C:12](=[O:13])[N:11]([CH3:14])[C:10](=[O:15])[C:9]([C:16]([OH:18])=O)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:21])=O>>[C:1]1([N:7]2[C:12](=[O:13])[N:11]([CH3:14])[C:10](=[O:15])[C:9]([C:16]([Cl:21])=[O:18])=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 15987642HCID 15987642, compound

Product 1

HCID 86696919HCID 86696919, compoundYield 87.5%

Procedure

Intermediate e (3 g, 0.012 mol) was added to thionyl chloride (10V/W, 30 mL). The mixture was warmed up to react under reflux for 6 h. The solvent was evaporated off to produce a clear yellow crystal (2.8 g) in a yield of 87.5%.

Workup

  1. temperatureThe mixture was warmed up
  2. customto react
  3. temperatureunder reflux for 6 h
  4. customThe solvent was evaporated off

Sources & evidence

ORD record
ord-3ace713c6dec4862bfafd89796939644
Source dataset
uspto-grants-2014_09
Patent number
US08822465B2

Reaction notes

Loading…