Hydroxide → 6-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-nicotinic acid
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][c:7]([NH:10][C:11]([CH:12]([CH:13]2[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]2)[n:19]2[c:20](-[c:30]3[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]3)[n:21][c:22]3[c:23]2[cH:24][c:25]([F:29])[c:26]([F:28])[cH:27]3)=[O:37])[cH:8][cH:9]1)=[O:38].[Li+:41].[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[OH-:40].[OH2:39].[OH2:42]>>[O:2]=[C:3]([c:4]1[cH:5][n:6][c:7]([NH:10][C:11]([CH:12]([CH:13]2[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]2)[n:19]2[c:20](-[c:30]3[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]3)[n:21][c:22]3[c:23]2[cH:24][c:25]([F:29])[c:26]([F:28])[cH:27]3)=[O:37])[cH:8][cH:9]1)[OH:38]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-62a72ad8ad8b4259a124682029b76433
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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