Dichloromethane → tert-butyl 4-allyl-4-(N-((1-tosyl-1H-indol-4-yl)methyl)acrylamido)piperidine-1-carboxylate
Reaction equation
[C:1]([CH:2]=[CH2:3])(=[O:4])[Cl:5].[CH2:6]([CH:7]=[CH2:8])[C:9]1([NH:22][CH2:23][c:24]2[c:25]3[cH:26][cH:27][n:28]([S:33](=[O:34])(=[O:35])[c:36]4[cH:37][cH:38][c:39]([CH3:40])[cH:41][cH:42]4)[c:29]3[cH:30][cH:31][cH:32]2)[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1.[CH:43]([N:44]([CH:45]([CH3:46])[CH3:47])[CH2:48][CH3:49])([CH3:50])[CH3:51].[Cl:52][CH2:53][Cl:54]>>[C:1]([CH:2]=[CH2:3])(=[O:4])[N:22]([C:9]1([CH2:6][CH:7]=[CH2:8])[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1)[CH2:23][c:24]1[c:25]2[cH:26][cH:27][n:28]([S:33](=[O:34])(=[O:35])[c:36]3[cH:37][cH:38][c:39]([CH3:40])[cH:41][cH:42]3)[c:29]2[cH:30][cH:31][cH:32]1Participants
5
Sources & evidence
- ORD record
- ord-d8c003a069c64d8095b50b58a852b6a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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