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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 685884Generated: October 30, 2026

Dimethyl Sulfoxide → 2-[3,5-Bis(trifluoromethyl)phenyl]-n{4-(4-fluoro-2-methylphenyl)-6-[8a-(hydroxymethyl)hexahydropyrrolo[1,2-a]pyrazin-2(1h)-yl]-3-pyridinyl}-n,2-dimethylpropanamide

https://huagongshe.com/reaction/685884

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantCarbonate IonHCID 19660—
Reactant2-(3,5-Bis(trifluoromethyl)phenyl)-N-(6-chloro-4-(4-fluoro-2-methylphenyl)pyrid-3-yl)-N,2-dimethylpropanamideHCID 23502784—
Reactant(Octahydropyrrolo[1,2-a]pyrazin-8a-yl)methanolHCID 45122045—
Product2-[3,5-Bis(trifluoromethyl)phenyl]-n{4-(4-fluoro-2-methylphenyl)-6-[8a-(hydroxymethyl)hexahydropyrrolo[1,2-a]pyrazin-2(1h)-yl]-3-pyridinyl}-n,2-dimethylpropanamideHCID 16064038—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-44ad4d6e28d247d38ea356faf520e1f3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)