Hydrochloric Acid → N-(3,4-dichlorophenyl)-7-[({2-[(dimethylamino)methyl]-1,3-thiazol-4-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[CH3:42][C:43]([O:44][I:45]1([O:55][C:56]([CH3:57])=[O:58])([O:59][C:60]([CH3:61])=[O:62])[c:46]2[c:47]([cH:48][cH:49][cH:50][cH:51]2)[C:52](=[O:53])[O:54]1)=[O:63].[Cl:14][c:15]1[cH:16][c:17]([NH:22][c:23]2[n:24][cH:25][n:26][c:27]3[cH:28][c:29]([OH:35])[c:30]([O:33][CH3:34])[cH:31][c:32]23)[cH:18][cH:19][c:20]1[Cl:21].[Cl:3][CH2:4][c:5]1[n:6][c:7]([CH2:10][N:11]([CH3:12])[CH3:13])[s:8][cH:9]1.[ClH:1].[ClH:2].[K+:40].[K+:41]>>[CH2:4]([c:5]1[n:6][c:7]([CH2:10][N:11]([CH3:12])[CH3:13])[s:8][cH:9]1)[O:35][c:29]1[cH:28][c:27]2[n:26][cH:25][n:24][c:23]([NH:22][c:17]3[cH:16][c:15]([Cl:14])[c:20]([Cl:21])[cH:19][cH:18]3)[c:32]2[cH:31][c:30]1[O:33][CH3:34]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-19cb0c7e12504cf7b1630effdff63a78
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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