Dichloromethane → 3-((5-(1H-indol-2-yl)oxazol-2-yl)amino)phenol

HRID 686452Notes

Reaction equation

HRID 686452 reaction equation
[Cl:37][CH2:38][Cl:39].[OH:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[o:10][c:11](-[c:14]3[n:15]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[c:16]4[cH:17][cH:18][cH:19][cH:20][c:21]4[cH:22]3)[cH:12][n:13]2)[cH:5][cH:6][cH:7]1.[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[OH:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[o:10][c:11](-[c:14]3[nH:15][c:16]4[cH:17][cH:18][cH:19][cH:20][c:21]4[cH:22]3)[cH:12][n:13]2)[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 71060496tert-butyl 2-(2-((3-hydroxyphenyl)amino)oxazol-5-yl)-1H-indole-1-carboxylate

Product 1

HCID 710604143-((5-(1H-indol-2-yl)oxazol-2-yl)amino)phenol

Sources & evidence

ORD record
ord-395f1aea193b4f078163ca003ca744ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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