Acetonitrile → [6-Chloro-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(4-cyclopropanecarbonyl-piperazin-1-yl)-methanone
Reaction equation
[C:29]([O-:30])([O-:31])=[O:32].[C:35]([Cl:36])([Cl:37])=[O:38].[CH2:39]1[CH2:40][CH2:41]1.[CH3:42][C:43]#[N:44].[Cl:1][c:2]1[c:3]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[nH:8][c:9]2[cH:10]1.[Cs+:33].[Cs+:34]>>[Cl:1][c:2]1[c:3]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][N:16]([C:29](=[O:32])[CH:39]4[CH2:40][CH2:41]4)[CH2:17][CH2:18]3)[nH:8][c:9]2[cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1ad3f5a8a77849539974da6ee9df7966
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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