Dimethylformamide → 2H-Naphth[2,3-b]-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR,10aR)-;2H-Naphth[2,3-b]-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR,10aR)-

HRID 686632Notes

Reaction equation

HRID 686632 reaction equation
[CH3:19][S:20][Li:21].[I:1][c:2]1[cH:3][cH:4][c:5]([O:17][CH3:18])[c:6]2[c:16]1[CH2:15][CH:9]1[CH:8]([CH2:7]2)[N:13]([CH3:14])[CH2:12][CH2:11][O:10]1.[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[c:2]1([S:20][CH3:19])[cH:3][cH:4][c:5]([O:17][CH3:18])[c:6]2[c:16]1[CH2:15][CH:9]1[CH:8]([CH2:7]2)[N:13]([CH3:14])[CH2:12][CH2:11][O:10]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 15131081(+/-)-4-Methyl-6-methoxy-9-iodo3,4,4a,5,10,10a-hexahydro-2H-naphto-[2,3-b][1,4]oxazineHCID 178418898HCID 178418898, compound

Product 1

HCID 151171322H-Naphth[2,3-b]-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR,10aR)-;2H-Naphth[2,3-b]-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR,10aR)-

Sources & evidence

ORD record
ord-30424d10d6f645ad9886ed3b5e4323f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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