HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Methoxy-1-phenyl-6-(3-piperazin-1-ylazetidin-1-yl)indazole;hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl 4-(azetidin-3-yl)piperazine-1-carboxylate | HCID 21183794 | — |
| Reactant | 6-Bromo-3-methoxy-1-phenyl-1H-indazole | HCID 67447175 | — |
| Product | 3-Methoxy-1-phenyl-6-(3-piperazin-1-ylazetidin-1-yl)indazole;hydrochloride | HCID 67449636 | — |
Reaction Steps
The title compound was prepared according to the procedure as described in Example 57 reacting 6-bromo-3-methoxy-1-phenyl-1H-indazole and 4-azetidin-3-yl-piperazine-1-carboxylic acid tert-butyl ester, followed by de-protection with HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822447B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-864a5cb0c3de48519624a71efca87960 |
| Source note | uspto-grants-2014_09 |