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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 68708Generated: October 29, 2026

Hydrochloric Acid → 6-(4-(Azetidin-3-yl)piperazin-1-yl)-3-methoxy-1-phenyl-1H-indazole hydrochloride

https://huagongshe.com/reaction/68708

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-Butyl 3-(piperazin-1-yl)azetidine-1-carboxylateHCID 19360775—
Reactant6-Bromo-3-methoxy-1-phenyl-1H-indazoleHCID 67447175—
Product6-(4-(Azetidin-3-yl)piperazin-1-yl)-3-methoxy-1-phenyl-1H-indazole hydrochlorideHCID 67448716—

Reaction Steps

The title compound was prepared according to the procedure as described in Example 57 reacting 6-bromo-3-methoxy-1-phenyl-1H-indazole and 3-piperazin-1-yl-azetidine-1-carboxylic acid tert-butyl ester, followed by de-protection with HCl.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822447B2
Source datasetuspto-grants-2014_09
ORD IDord-4d8e62c0be8a4dbea223a33ef1c3fc3d
Source noteuspto-grants-2014_09