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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 68709Generated: October 29, 2026

Hydrochloric Acid → 3-Methoxy-1-phenyl-6-(4-(pyrrolidin-3-yl)piperazin-1-yl)-1H-indazole hydrochloride

https://huagongshe.com/reaction/68709

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTert-butyl 3-(piperazin-1-yl)pyrrolidine-1-carboxylateHCID 53216205—
Reactant6-Bromo-3-methoxy-1-phenyl-1H-indazoleHCID 67447175—
Product3-Methoxy-1-phenyl-6-(4-(pyrrolidin-3-yl)piperazin-1-yl)-1H-indazole hydrochlorideHCID 67447299—

Reaction Steps

The title compound was prepared according to the procedure as described in Example 57 reacting 6-bromo-3-methoxy-1-phenyl-1H-indazole and 3-piperazin-1-yl-pyrrolidine-1-carboxylic acid tert-butyl ester, followed by de-protection with HCl.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822447B2
Source datasetuspto-grants-2014_09
ORD IDord-b7414d30f3714c1bb62762d004a63e9e
Source noteuspto-grants-2014_09