反应详情

A 250-mL 3-necked round-bottom flask was purged, was added a solution of 3-methoxy-6-nitro-1-phenyl-1H-indazole (800 mg, 2.91 mmol, 1.00 equiv, 98%) in tetrahydrofuran (125 mL), palladium carbon (0.1 g), then flushed and maintained with a hydrogen atmosphere. The resulting solution was stirred for 5 min at room temperature. The solids were filtered out. The resulting mixture was concentrated under vacuum to yield 3-methoxy-1-phenyl-1H-indazol-6-amine as a gray solid. MS (m/z): 240 [MH+].

1. customA 250-mL 3-necked round-bottom flask was purged
2. customflushed
3. temperaturemaintained with a hydrogen atmosphere
4. filtrationThe solids were filtered out
5. concentrationThe resulting mixture was concentrated under vacuum