Ethanol → 4-Fluoro-1-(5-methoxy-4,6-dimethylpyridin-2-yl)-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]2([c:19]3[n:20][c:21]([CH3:28])[c:22]([O:26][CH3:27])[c:23]([CH3:25])[cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1.[C:38](=[O:39])([O-:40])[O-:41].[CH3:44][CH2:45][O:46][C:47]([CH3:48])=[O:49].[CH3:50][O:51][CH2:52][CH2:53][O:54][CH3:55].[CH3:56][CH2:57][OH:58].[Cs+:42].[Cs+:43].[OH2:59].[OH2:60].[n:29]1[cH:30][n:31][cH:32][c:33]([B:35]([OH:36])[OH:37])[cH:34]1>>[c:2]1(-[c:33]2[cH:32][n:31][cH:30][n:29][cH:34]2)[cH:3][c:4]([C:8]2([c:19]3[n:20][c:21]([CH3:28])[c:22]([O:26][CH3:27])[c:23]([CH3:25])[cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-724e5cd96ae5483985a51f8c45939ec8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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