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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 687160Generated: November 1, 2026

Ammonium → (3aRS,4RS,6SR,7aSR)-6-hydroxymethyl-4-(2-fluorophenyl)-2-tert-butyloxycarbonylperhydroisoindol 4-ol

https://huagongshe.com/reaction/687160

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
Reactant1-Bromo-2-fluorobenzeneHCID 61259—
Reactant(3aRS,6SR,7aSR)-6-hydroxymethyl-2-tert-butyloxycarbonylperhydroisoindol-4-oneHCID 18931561—
ReactantButyllithiumHCID 178418339—
Product(3aRS,4RS,6SR,7aSR)-6-hydroxymethyl-4-(2-fluorophenyl)-2-tert-butyloxycarbonylperhydroisoindol 4-olHCID 67661831—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-6e203afc1a1d4ffca374560b187a4717
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)