Ammonium → (3aRS,4RS,6SR,7aSR)-6-hydroxymethyl-4-(2-fluorophenyl)-2-tert-butyloxycarbonylperhydroisoindol 4-ol
Reaction equation
[CH3:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[Cl-:33].[F:6][c:7]1[c:8]([Br:13])[cH:9][cH:10][cH:11][cH:12]1.[Li:1][CH2:2][CH2:3][CH2:4][CH3:5].[NH4+:34].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH:14][CH2:15][CH:16]1[CH2:17][C:18](=[O:32])[CH:19]2[CH2:20][N:21]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH:23]2[CH2:24]1>>[F:6][c:7]1[c:8]([C:18]2([OH:32])[CH2:17][CH:16]([CH2:15][OH:14])[CH2:24][CH:23]3[CH:19]2[CH2:20][N:21]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22]3)[cH:9][cH:10][cH:11][cH:12]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-6e203afc1a1d4ffca374560b187a4717
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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