HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-(4-Methyl-oxazol-5-yl)-benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(4-Methyloxazol-5-yl)benzoic acid | HCID 68290055 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-Methyl-oxazol-5-yl)-benzoyl chloride | HCID 86678211 | — |
Reaction Steps
Thionyl chloride (2.00 mL) is added to 4-(4-methyl-oxazol-5-yl)-benzoic acid (400 mg) in dichloromethane (5 mL) and the mixture is stirred for two days at room temperature. The solvent is evaporated to give the title compound, which is used without further purification for the next reaction step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-00937668ffff45a6bfe0b720f329e30d |
| Source note | uspto-grants-2014_09 |