Dimethyl Sulfoxide → 2-(4-Chloro-3-fluorophenyl)-2-methyloxirane

HRID 687644Notes

Reaction equation

HRID 687644 reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:1][S:2]([CH3:3])=[O:4].[CH3:8][S+:9]([CH3:10])[CH3:11].[Cl:12][c:13]1[c:14]([F:22])[cH:15][c:16]([C:19]([CH3:20])=[O:21])[cH:17][cH:18]1.[H-:6].[I-:7].[Na+:5].[OH2:28]>>[CH3:8][C:19]1([c:16]2[cH:15][c:14]([F:22])[c:13]([Cl:12])[cH:18][cH:17]2)[CH2:20][O:21]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 962WaterHCID 1147TrimethylsulfoniumHCID 8028TetrahydrofuranHCID 30165Iodide IonHCID 166653HydrideHCID 38220774'-Chloro-3'-fluoroacetophenone

Product 1

HCID 594551652-(4-Chloro-3-fluorophenyl)-2-methyloxirane

Sources & evidence

ORD record
ord-afb9bc97e6124436a5cc2ec3e362e86e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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