HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Trifluoroacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-{Cyclopropyl-[4-(4-methyl-oxazol-5-yl)-benzoyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester | HCID 68289892 | — |
| Product | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 68289917 | HCID 68289917 | — |
Reaction Steps
A mixture of 4-{cyclopropyl-[4-(4-methyl-oxazol-5-yl)-benzoyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester (180 mg) and trifluoroacetic acid (20% in dichloromethane) is stirred for 1 h at room temperature. The solvent is evaporated to give the title compound as its trifluoroacetic acid salt. Mass spectrum (ESI+): m/z=326 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-f8d90795529c4936bda47a00fc657b43 |
| Source note | uspto-grants-2014_09 |