Toluene → 6-[4-({[6-(3-Fluorophenyl)pyridin-3-yl]carbonyl}amino)piperidin-1-yl]nicotinic acid
Reaction equation
[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[Cl:36][CH2:37][Cl:38].[F:1][c:2]1[cH:3][c:4](-[c:8]2[cH:9][cH:10][c:11]([C:14](=[O:15])[NH:16][CH:17]3[CH2:18][CH2:19][N:20]([c:23]4[n:24][cH:25][c:26]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[cH:34][cH:35]4)[CH2:21][CH2:22]3)[cH:12][n:13]2)[cH:5][cH:6][cH:7]1.[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[F:1][c:2]1[cH:3][c:4](-[c:8]2[cH:9][cH:10][c:11]([C:14](=[O:15])[NH:16][CH:17]3[CH2:18][CH2:19][N:20]([c:23]4[n:24][cH:25][c:26]([C:27](=[O:28])[OH:29])[cH:34][cH:35]4)[CH2:21][CH2:22]3)[cH:12][n:13]2)[cH:5][cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-bc2f9fe4baf741198a79682fb1d0a6e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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