HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-3-pyridinecarbonitrile → N-[1-(5-Cyano-pyridin-2-yl)-piperidin-4-yl]-N-cyclopropyl-4-oxazol-5-yl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-3-pyridinecarbonitrile | HCID 5152094 | — |
| Reactant | N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide | HCID 68289931 | — |
| Product | N-[1-(5-Cyano-pyridin-2-yl)-piperidin-4-yl]-N-cyclopropyl-4-oxazol-5-yl-benzamide | HCID 68351870 | — |
Reaction Steps
The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 6-chloro-nicotinonitrile following a procedure analogous to that described in Example 19. LC (method 9): tR=2.02 min; Mass spectrum (ESI+): m/z=414 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-5ab9f93d2fa54335a4e0c08edcececb7 |
| Source note | uspto-grants-2014_09 |