2-Chloro-5-(4-chlorophenyl)pyrimidine → N-{1-[5-(4-Chloro-phenyl)-pyrimidin-2-yl]-piperidin-4-yl}-N-cyclopropyl-4-oxazol-5-yl-benzamide

Participants

Role	Name	HCID	Charge
Reactant	2-Chloro-5-(4-chlorophenyl)pyrimidine	HCID 2761025	—
Reactant	N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide	HCID 68289931	—
Product	N-{1-[5-(4-Chloro-phenyl)-pyrimidin-2-yl]-piperidin-4-yl}-N-cyclopropyl-4-oxazol-5-yl-benzamide	HCID 68351869	—

Reaction Steps

The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-chloro-5-(4-chloro-phenyl)-pyrimidine following a procedure analogous to that described in Example 19. LC (method 9): tR=2.42 min; Mass spectrum (ESI+): m/z=500/502 (Cl) [M+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08822471B2
Source dataset	uspto-grants-2014_09
ORD ID	ord-2b95c79a432c48149477287174ed0cd2
Source note	uspto-grants-2014_09