Trimethylsilylacetylene → N-[4-Chloro-7-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethyl)-5-trimethylsilanylethynyl-7H-pyrrolo [2,3-d]pyrimidin-2-yl]-2,2-dimethyl-propionamide
Reaction equation
[C:30](#[CH:31])[Si:32]([CH3:33])([CH3:34])[CH3:35].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[n:7]1)[n:15]([CH2:19][c:20]1[n:21][cH:22][c:23]([CH3:29])[c:24]([O:27][CH3:28])[c:25]1[CH3:26])[cH:16][c:17]2[I:18]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[n:7]1)[n:15]([CH2:19][c:20]1[n:21][cH:22][c:23]([CH3:29])[c:24]([O:27][CH3:28])[c:25]1[CH3:26])[cH:16][c:17]2[C:31]#[C:30][Si:32]([CH3:33])([CH3:34])[CH3:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0e66dba7e2094c99b4f946db26e639de
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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