2-Fluoropyridine → HCID 68289764, compound

HRID 68828Notes

Reaction equation

HRID 68828 reaction equation
[CH:1]1([N:4]([CH:18]2[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]2)[C:5](=[O:17])[C:6]2[CH:11]=[CH:10][C:9]([C:12]3[O:16][CH:15]=[N:14][CH:13]=3)=[CH:8][CH:7]=2)[CH2:3][CH2:2]1.F[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=1>>[CH:1]1([N:4]([CH:18]2[CH2:23][CH2:22][N:21]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=3)[CH2:20][CH2:19]2)[C:5](=[O:17])[C:6]2[CH:7]=[CH:8][C:9]([C:12]3[O:16][CH:15]=[N:14][CH:13]=3)=[CH:10][CH:11]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 97462-FluoropyridineHCID 68289931N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide

Product 1

HCID 68289764HCID 68289764, compound

Procedure

The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-fluoro-pyridine following a procedure analogous to that described in Example 19. LC (method 9): tR=1.46 min; Mass spectrum (ESI+): m/z=389 [M+H]+.

Sources & evidence

ORD record
ord-9e1dfc39b3f9431eb3fba205c6747006
Source dataset
uspto-grants-2014_09
Patent number
US08822471B2

Reaction notes

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