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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 688352Generated: October 26, 2026

Tetrahydrofuran → 5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)-pyridin-2-amine

https://huagongshe.com/reaction/688352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantCopper iodideHCID 83717—
Reactant3-Iodo-5-(trifluoromethyl)pyridin-2-amineHCID 15350914—
Product5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)-pyridin-2-amineHCID 46736871—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-73ed2175255c447cb12ce54893b5e3b8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)