Tetrahydrofuran → 5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)-pyridin-2-amine
Reaction equation
[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH3:24][CH2:25][O:26][C:27](=[O:28])[CH3:29].[Cu:30]([I:31])[I:32].[I:1][c:2]1[c:3]([NH2:12])[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Si:13]([CH3:14])([CH3:15])([CH3:16])[C:17]#[CH:18]>>[c:2]1([C:18]#[C:17][Si:13]([CH3:14])([CH3:15])[CH3:16])[c:3]([NH2:12])[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-73ed2175255c447cb12ce54893b5e3b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…