HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-cyclopropyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)piperidin-4-amine → N-Cyclopropyl-4-(4-methyl-oxazol-5-yl)-N-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-cyclopropyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)piperidin-4-amine | HCID 68289604 | — |
| Reactant | 4-(4-Methyloxazol-5-yl)benzoic acid | HCID 68290055 | — |
| Product | N-Cyclopropyl-4-(4-methyl-oxazol-5-yl)-N-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-benzamide | HCID 68351854 | — |
Reaction Steps
The title compound is prepared from cyclopropyl-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amine and 4-(4-methyl-oxazol-5-yl)-benzoic acid following a procedure analogous to that described in Example 17. LC (method 11): tR=3.12 min; Mass spectrum (ESI+): m/z=470 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-671562f25a214a428941780ede682175 |
| Source note | uspto-grants-2014_09 |