Acetonitrile → 2-Chloro-6-[(2,2-dimethyl-propyl)-amino]-5-fluoro-nicotinonitrile
Reaction equation
[CH2:12]([C:13]([CH3:14])([CH3:15])[CH3:16])[NH2:17].[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:25][C:26]#[N:27].[Cl:1][c:2]1[n:3][c:4]([Cl:11])[c:5]([F:10])[cH:6][c:7]1[C:8]#[N:9]>>[Cl:1][c:2]1[n:3][c:4]([NH:17][CH2:12][C:13]([CH3:14])([CH3:15])[CH3:16])[c:5]([F:10])[cH:6][c:7]1[C:8]#[N:9]Participants
5
Sources & evidence
- ORD record
- ord-56916f9628864d00bf6f1cb46653b850
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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