N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide → N-Cyclopropyl-N-{1-[3-(2-hydroxy-1,1-dimethyl-ethyl)-[1,2,4]oxadiazol-5-yl]-piperidin-4-yl}-4-oxazol-5-yl-benzamide

Participants

Reaction Steps

The title compound is prepared from N-(1-cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide and 3,N-dihydroxy-2,2-dimethyl-propionamidine following a procedure analogous to that described in Example 1. LC (method 1): tR=1.08 min; Mass spectrum (ESI+): m/z=452 [M+H]+.

Provenance & Evidence