Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-5-ethylpyrimidine → N-Cyclopropyl-N-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-3-fluoro-4-oxazol-5-yl-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| 반응물 | N-Cyclopropyl-3-fluoro-4-oxazol-5-yl-N-piperidin-4-yl-benzamide | HCID 68290215 | — |
| 생성물 | N-Cyclopropyl-N-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-3-fluoro-4-oxazol-5-yl-benzamide | HCID 68290892 | — |
반응 단계
The title compound is prepared from N-cyclopropyl-3-fluoro-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described in Example 19. LC (method 1): tR=1.16 min; Mass spectrum (ESI+): m/z=436 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822471B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-065cbdc2fd3a42a08be6a218ff307e59 |
| 출처 메모 | uspto-grants-2014_09 |