HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2,5-dimethylpyrazine → HCID 68290682, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2,5-dimethylpyrazine | HCID 66771 | — |
| Reactant | N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide hydrochloride | HCID 68289930 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 68290682 | HCID 68290682 | — |
Reaction Steps
The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide hydrochloride and 3-chloro-2,5-dimethyl-pyrazine following a procedure analogous to that described in Example 19 using N-methylpyrrolidinone as solvent. LC (method 16): tR=0.44 min; Mass spectrum (ESI+): m/z=418 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-cfab1e2425864cb3b9cc5746d7165396 |
| Source note | uspto-grants-2014_09 |