Dichloromethane → 4-amino-N-(3-amino-1-(4-chlorophenyl)propyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Reaction equation
[Cl:45][CH2:46][Cl:47].[NH2:8][CH2:9][CH2:10][CH:11]([c:12]1[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]1)[NH:19][C:20](=[O:21])[C:22]1([NH:37][C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:23][CH2:24][N:25]([c:28]2[c:29]3[c:30]([n:31][cH:32][n:33]2)[nH:34][cH:35][cH:36]3)[CH2:26][CH2:27]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH2:8][CH2:9][CH2:10][CH:11]([c:12]1[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]1)[NH:19][C:20](=[O:21])[C:22]1([NH2:37])[CH2:23][CH2:24][N:25]([c:28]2[c:29]3[c:30]([n:31][cH:32][n:33]2)[nH:34][cH:35][cH:36]3)[CH2:26][CH2:27]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-178b017729a649bb98b0dac370a5fad3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…