HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Methyl-1H-1,2,4-triazol-1-yl)benzoic acid → N-Cyclopropyl-N-[1-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-4-(5-methyl-[1,2,4]triazol-1-yl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Methyl-1H-1,2,4-triazol-1-yl)benzoic acid | HCID 68289587 | — |
| Reactant | N-cyclopropyl-1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-amine | HCID 68290028 | — |
| Product | N-Cyclopropyl-N-[1-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-4-(5-methyl-[1,2,4]triazol-1-yl)-benzamide | HCID 71293507 | — |
Reaction Steps
The title compound is prepared from cyclopropyl-[1-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amine and 4-(5-methyl-[1,2,4]triazol-1-yl)-benzoic acid following a procedure analogous to that described in Example 90. LC (method 19): tR=3.30 min; Mass spectrum (ESI+): m/z=436 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-431b0787257a4482bed1cc0051719a00 |
| Source note | uspto-grants-2014_09 |