HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-methyl-1H-imidazol-1-yl)benzoic acid → N-Cyclopropyl-N-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-4-(2-methyl-imidazol-1-yl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-methyl-1H-imidazol-1-yl)benzoic acid | HCID 13815988 | — |
| Reactant | N-cyclopropyl-1-(5-ethylpyrimidin-2-yl)piperidin-4-amine | HCID 68289588 | — |
| Product | N-Cyclopropyl-N-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-4-(2-methyl-imidazol-1-yl)-benzamide | HCID 68290608 | — |
Reaction Steps
The title compound is prepared from cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-amine and 4-(2-methyl-imidazol-1-yl)-benzoic acid following a procedure analogous to that described in Example 90. LC (method 19): tR=3.84 min; Mass spectrum (ESI+): m/z=431 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-c803a2d3f3b741d88d1f78a50f0235ba |
| Source note | uspto-grants-2014_09 |