4-(5-methyl-1H-1,2,3,4-tetrazol-1-yl)benzoic acid → N-[1-(5-Chloro-pyrimidin-2-yl)-piperidin-4-yl]-N-cyclopropyl-4-(5-methyl-tetrazol-1-yl)-benzamide

Participants

Role	Name	HCID	Charge
Reactant	4-(5-methyl-1H-1,2,3,4-tetrazol-1-yl)benzoic acid	HCID 3155249	—
Reactant	1-(5-chloropyrimidin-2-yl)-N-cyclopropylpiperidin-4-amine	HCID 68289573	—
Product	N-[1-(5-Chloro-pyrimidin-2-yl)-piperidin-4-yl]-N-cyclopropyl-4-(5-methyl-tetrazol-1-yl)-benzamide	HCID 68290744	—

Reaction Steps

The title compound is prepared from [1-(5-chloro-pyrimidin-2-yl)-piperidin-4-yl]-cyclopropyl-amine and 4-(5-methyl-tetrazol-1-yl)-benzoic acid following a procedure analogous to that described in Example 107. LC (method 19): tR=4.02 min; Mass spectrum (ESI+): m/z=439 [M+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08822471B2
Source dataset	uspto-grants-2014_09
ORD ID	ord-f529d28287d6460eae53928b1f69dc17
Source note	uspto-grants-2014_09