Boronic Acid → tert-Butyl {4-[(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(4'-formyl-4-methoxy-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate
Reaction equation
[BH:1]([OH:2])[OH:3].[Br:43][c:44]1[cH:45][cH:46][c:47]([CH:48]=[O:49])[cH:50][cH:51]1.[C:4](=[O:5])([O:6][C:7]([CH3:8])([CH3:9])[CH3:10])[N:11]([CH:12]1[CH2:13][CH2:14][CH:15]([N:18]([C:19](=[O:20])[c:21]2[c:22]([Cl:32])[c:23]3[c:24]([s:25]2)[c:26]([F:31])[cH:27][cH:28][c:29]3[F:30])[CH2:33][c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2[O:40][CH3:41])[CH2:16][CH2:17]1)[CH3:42]>>[C:4](=[O:5])([O:6][C:7]([CH3:8])([CH3:9])[CH3:10])[N:11]([CH:12]1[CH2:13][CH2:14][CH:15]([N:18]([C:19](=[O:20])[c:21]2[c:22]([Cl:32])[c:23]3[c:24]([s:25]2)[c:26]([F:31])[cH:27][cH:28][c:29]3[F:30])[CH2:33][c:34]2[cH:35][c:36](-[c:44]3[cH:45][cH:46][c:47]([CH:48]=[O:49])[cH:50][cH:51]3)[cH:37][cH:38][c:39]2[O:40][CH3:41])[CH2:16][CH2:17]1)[CH3:42]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7086e5e2dc0c4ec59b64b107e43785b0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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