Tetrahydrofuran → 4-(2-Bromo-1,3-thiazol-5-yl)-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidine
Reaction equation
[C:28]([Br:29])([Br:30])([Br:31])[Br:32].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38].[s:6]1[cH:7][n:8][cH:9][c:10]1-[c:11]1[c:12]2[c:13]([n:14][cH:15][n:16]1)[n:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:18][cH:19]2>>[s:6]1[c:7]([Br:29])[n:8][cH:9][c:10]1-[c:11]1[c:12]2[c:13]([n:14][cH:15][n:16]1)[n:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:18][cH:19]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6e15933d88a6421abcbf8433903b3138
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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