Diethyl Ether → 2-(4-Chlorophenyl)-2,2-difluoroethanol
Reaction equation
[Al+3:2].[CH3:22][CH2:23][O:24][CH2:25][CH3:26].[Cl:7][c:8]1[cH:9][cH:10][c:11]([C:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])([F:20])[F:21])[cH:12][cH:13]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[Cl:7][c:8]1[cH:9][cH:10][c:11]([C:14]([CH2:15][OH:16])([F:20])[F:21])[cH:12][cH:13]1Participants
6
Sources & evidence
- ORD record
- ord-978f963490a24c189b3c19351309c32f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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