Dichloromethane → 4-(Azetidin-3-yl)thiomorpholine 1,1-dioxide

HRID 689417Notes

Reaction equation

HRID 689417 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:12]2[CH2:13][CH2:14][S:15](=[O:18])(=[O:19])[CH2:16][CH2:17]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[Cl:27][CH2:28][Cl:29].[F:20][C:21]([F:22])([F:23])[C:24]([OH:25])=[O:26]>>[NH:8]1[CH2:9][CH:10]([N:12]2[CH2:13][CH2:14][S:15](=[O:18])(=[O:19])[CH2:16][CH2:17]2)[CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 596054113-(1,1-Dioxo-1-thiomorpholine-4-YL)azetidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 597519614-(Azetidin-3-yl)thiomorpholine 1,1-dioxide

Sources & evidence

ORD record
ord-33f2ce8ec1f440dbb7ac5e54cf764481
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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